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Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway

Loss of olfactomedin 4 (OLFM4) gene expression is associated with the progression of human prostate cancer, but its role and the molecular mechanisms involved in this process have not been completely understood. In this study, we found that Olfm4-knockout mice developed prostatic intraepithelial neo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Hongzhen, Liu, Wenli, Chen, Weiping, Zhu, Jianqiong, Deng, Chu-Xia, Rodgers, Griffin P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652203/
https://ncbi.nlm.nih.gov/pubmed/26581960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16974
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