Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway Activation

Despite significant investments in cancer research and drug discovery/development, the rate of new cancer drug approval is ≤5% and most cases of metastatic cancer remain incurable. Ninety-five percent of new cancer drugs fail in clinical development because of a lack of therapeutic efficacy and/or u...

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Bibliografiske detaljer
Udgivet i:Assay Drug Dev Technol
Main Authors: Singh, Manjulata, Close, David A., Mukundan, Shilpaa, Johnston, Paul A., Sant, Shilpa
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2015
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652144/
https://ncbi.nlm.nih.gov/pubmed/26274587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.662
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