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Elevated Plasma Marinobufagenin, An Endogenous Cardiotonic Steroid, Is Associated with Right Ventricular Dysfunction and Nitrative Stress in Heart Failure

BACKGROUND: Plasma levels of cardiotonic steroids (CTS) are elevated in volume-expanded states such as chronic kidney disease, but the role of these natriuretic hormones in subjects with heart failure (HF) is unclear. We sought to determine the prognostic role of the CTS marinobufagenin (MBG) in HF,...

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Detalhes bibliográficos
Publicado no:Circ Heart Fail
Main Authors: Kennedy, David J., Shrestha, Kevin, Sheehey, Brendan, Li, Xinmin S., Guggilam, Anuradha, Wu, Yuping, Finucan, Michael, Gabi, Alaa, Medert, Charles M., Westfall, Kristen, Borowski, Allen, Fedorova, Olga, Bagrov, Alexei Y., Tang, W.H. Wilson
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651837/
https://ncbi.nlm.nih.gov/pubmed/26276886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001976
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