Site Specific Modification of the Human Plasma Proteome by Methylglyoxal

Increasing evidence identifies dicarbonyl stress from reactive glucose metabolites, such as methylglyoxal (MG), as a major pathogenic link between hyperglycemia and complications of diabetes. MG covalently modifies arginine residues, yet the site specificity of this modification has not been thoroug...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Toxicol Appl Pharmacol
Main Authors: Kimzey, Michael J., Kinsky, Owen R., Yassine, Hussein N., Tsaprailis, George, Stump, Craig, Monks, Terrence J., Lau, Serrine S.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651758/
https://ncbi.nlm.nih.gov/pubmed/26435215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.09.029
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