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Site Specific Modification of the Human Plasma Proteome by Methylglyoxal
Increasing evidence identifies dicarbonyl stress from reactive glucose metabolites, such as methylglyoxal (MG), as a major pathogenic link between hyperglycemia and complications of diabetes. MG covalently modifies arginine residues, yet the site specificity of this modification has not been thoroug...
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Publicado no: | Toxicol Appl Pharmacol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4651758/ https://ncbi.nlm.nih.gov/pubmed/26435215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.09.029 |
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