In Oesophageal Squamous Cells, Nitric Oxide Causes S-Nitrosylation of Akt and Blocks SOX2 (Sex Determining Region Y-Box 2) Expression

OBJECTIVE: Barrett’s metaplasia might develop if GORD causes oesophageal squamous cells to convert into columnar cells. Acid and bile exposures upregulate columnar differentiation genes like CDX2 in oesophageal squamous cells, but it is not known if such exposures downregulate squamous differentiati...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Gut
Hlavní autoři: Asanuma, Kiyotaka, Huo, Xiaofang, Agoston, Agoston, Zhang, Xi, Yu, Chunhua, Cheng, Edaire, Zhang, Qiuyang, Dunbar, Kerry B., Pham, Thai H., Wang, David H., Iijima, Katsunori, Shimosegawa, Tooru, Odze, Robert D., Spechler, Stuart J., Souza, Rhonda F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651671/
https://ncbi.nlm.nih.gov/pubmed/25986942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2015-309272
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky