In Oesophageal Squamous Cells Exposed to Acidic Bile Salt Medium, Omeprazole Inhibits IL-8 Expression through Effects on Nuclear Factor-κB and Activator Protein-1

OBJECTIVE: Oesophagitis might result from the effects of chemokines produced by oesophageal cells in response to gastro-oesophageal reflux, and not solely from the direct, caustic effects of refluxed gastric juice. Proton pump inhibitors (PPIs) can block chemokine production through mechanisms indep...

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Detalhes bibliográficos
Main Authors: Huo, Xiaofang, Zhang, Xi, Yu, Chunhua, Zhang, Qiuyang, Cheng, Edaire, Wang, David H., Pham, Thai H., Spechler, Stuart J., Souza, Rhonda F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959621/
https://ncbi.nlm.nih.gov/pubmed/24048734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-305533
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