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The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer

OBJECTIVES: Lung cancer is the leading cause of cancer-related deaths worldwide. Overall 5-year survival has shown little improvement over the last decades. Seven in absentia homolog (SIAH) proteins are E3 ubiquitin ligases that mediate proteasomal protein degradation by poly-ubiquitination. Even th...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Moreno, Paula, Lara-Chica, Maribel, Soler-Torronteras, Rafael, Caro, Teresa, Medina, Manuel, Álvarez, Antonio, Salvatierra, Ángel, Muñoz, Eduardo, Calzado, Marco A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651316/
https://ncbi.nlm.nih.gov/pubmed/26580787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143376
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