Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood–brain barrier in rats

Partly due to poor blood–brain barrier drug penetration the treatment options for many brain diseases are limited. To safely enhance drug delivery to the brain, glutathione PEGylated liposomes (G-Technology®) were developed. In this study, in rats, we compared the pharmacokinetics and organ distribu...

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Bibliografiske detaljer
Udgivet i:J Drug Target
Main Authors: Rip, Jaap, Chen, Linda, Hartman, Robin, van den Heuvel, Angelique, Reijerkerk, Arie, van Kregten, Joan, van der Boom, Burt, Appeldoorn, Chantal, de Boer, Marco, Maussang, David, de Lange, Elizabeth C. M., Gaillard, Pieter J.
Format: Artigo
Sprog:Inglês
Udgivet: Informa UK Ltd. 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651142/
https://ncbi.nlm.nih.gov/pubmed/24524555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1061186X.2014.888070
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