Herpes Simplex Virus Vector-Mediated Gene Delivery of Poreless TRPV1 Channels Reduces Bladder Overactivity and Nociception in Rats

Increased afferent excitability has been proposed as an important pathophysiology of interstitial cystitis/bladder pain syndrome (IC/BPS) and overactive bladder (OAB). In this study, we investigated whether herpes simplex virus (HSV) vectors encoding poreless TRPV1, in which the segment in C terminu...

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Bibliografski detalji
Izdano u:Hum Gene Ther
Glavni autori: Majima, Tsuyoshi, Funahashi, Yasuhito, Takai, Shun, Goins, William F., Gotoh, Momokazu, Tyagi, Pradeep, Glorioso, Joseph C., Yoshimura, Naoki
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651024/
https://ncbi.nlm.nih.gov/pubmed/26204493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.026
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