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Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration
BACKGROUND: Microglia reactivity is a hallmark of retinal degenerations and overwhelming microglial responses contribute to photoreceptor death. Minocycline, a semi-synthetic tetracycline analog, has potent anti-inflammatory and neuroprotective effects. Here, we investigated how minocycline affects...
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| 發表在: | J Neuroinflammation |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4650866/ https://ncbi.nlm.nih.gov/pubmed/26576678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0431-4 |
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