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Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons
Sigma-1 receptor (σ(1)R) has been reported to be decreased in nigrostriatal motor system of Parkinson's disease patients. Using heterozygous and homozygous σ(1)R knockout (σ(1)R(+/−) and σ(1)R(−/−)) mice, we investigated the influence of σ(1)R deficiency on 1-methyl-4-phenyl-1,2,3,6-tetrahydrop...
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| Publicat a: | Cell Death Dis |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4650739/ https://ncbi.nlm.nih.gov/pubmed/26203861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.194 |
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