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Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer

CD133 and CXCR4 were evaluated in the NCI-60 cell lines to identify cancer stem cell rich populations. Screening revealed that, ovarian OVCAR-3, -4 and -5 and colon cancer HT-29, HCT-116 and SW620 over expressed both proteins. We aimed to isolate cells with stem cell features sorting the cells expre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cioffi, Michele, D’Alterio, Crescenzo, Camerlingo, Rosalba, Tirino, Virginia, Consales, Claudia, Riccio, Anna, Ieranò, Caterina, Cecere, Sabrina Chiara, Losito, Nunzia Simona, Greggi, Stefano, Pignata, Sandro, Pirozzi, Giuseppe, Scala, Stefania
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650662/
https://ncbi.nlm.nih.gov/pubmed/26020117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10357
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