The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters

Recent studies have boosted our understanding of long noncoding RNAs (lncRNAs) in numerous biological processes, but few have examined their roles in somatic cell reprogramming. Through expression profiling and functional screening, we have identified that the large intergenic noncoding RNA p21 (lin...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Bao, Xichen, Wu, Haitao, Zhu, Xihua, Guo, Xiangpeng, Hutchins, Andrew P, Luo, Zhiwei, Song, Hong, Chen, Yongqiang, Lai, Keyu, Yin, Menghui, Xu, Lingxiao, Zhou, Liang, Chen, Jiekai, Wang, Dongye, Qin, Baoming, Frampton, Jon, Tse, Hung-Fat, Pei, Duanqing, Wang, Huating, Zhang, Biliang, Esteban, Miguel A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650593/
https://ncbi.nlm.nih.gov/pubmed/25512341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.165
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