Spermidine promotes retinal ganglion cell survival and optic nerve regeneration in adult mice following optic nerve injury

Spermidine acts as an endogenous free radical scavenger and inhibits the action of reactive oxygen species. In this study, we examined the effects of spermidine on retinal ganglion cell (RGC) death in a mouse model of optic nerve injury (ONI). Daily ingestion of spermidine reduced RGC death followin...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Noro, T, Namekata, K, Kimura, A, Guo, X, Azuchi, Y, Harada, C, Nakano, T, Tsuneoka, H, Harada, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650557/
https://ncbi.nlm.nih.gov/pubmed/25880087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.93
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