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miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway
BACKGROUND: Drug resistance hampers the efficient treatment of malignancies, including advanced stage ovarian cancer, which has a 5-year survival rate of only 30 %. The molecular processes underlying resistance have been extensively studied, however, not much is known about the involvement of microR...
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Gepubliceerd in: | Mol Cancer |
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Hoofdauteurs: | , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
BioMed Central
2015
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4650519/ https://ncbi.nlm.nih.gov/pubmed/26576679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0464-4 |
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