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miR-449a targets Flot2 and inhibits gastric cancer invasion by inhibiting TGF-β-mediated EMT

BACKGROUND: Flot2, a highly conserved protein of the SPFH domain containing proteins family, has recently been identified as oncogene to be involved in the tumorigenesis and metastasis of several cancers including gastric cancer. However, the underlying molecular mechanism of Flot2 in gastric cancer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Diagn Pathol
Hauptverfasser: Li, Qian, Peng, Jie, Li, Xinhua, Leng, Aimin, Liu, Ting
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650491/
https://ncbi.nlm.nih.gov/pubmed/26576674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0435-5
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