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miR-449a targets Flot2 and inhibits gastric cancer invasion by inhibiting TGF-β-mediated EMT

BACKGROUND: Flot2, a highly conserved protein of the SPFH domain containing proteins family, has recently been identified as oncogene to be involved in the tumorigenesis and metastasis of several cancers including gastric cancer. However, the underlying molecular mechanism of Flot2 in gastric cancer...

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Bibliographic Details
Published in:Diagn Pathol
Main Authors: Li, Qian, Peng, Jie, Li, Xinhua, Leng, Aimin, Liu, Ting
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650491/
https://ncbi.nlm.nih.gov/pubmed/26576674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0435-5
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