Absence of RIPK3 predicts necroptosis resistance in malignant melanoma

Acquired or intrinsic resistance to apoptotic and necroptotic stimuli is considered a major hindrance of therapeutic success in malignant melanoma. Inhibitor of apoptosis proteins (IAPs) are important regulators of apoptotic and necroptotic cell death mediated by numerous cell death signalling platf...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Geserick, P, Wang, J, Schilling, R, Horn, S, Harris, P A, Bertin, J, Gough, P J, Feoktistova, M, Leverkus, M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650439/
https://ncbi.nlm.nih.gov/pubmed/26355347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.240
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