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Homeostatic regulation of h‐conductance controls intrinsic excitability and stabilizes the threshold for synaptic modification in CA1 neurons

KEY POINTS: We determined the contribution of the hyperpolarization‐activated cationic (h) current (I (h)) to the homeostatic regulation of CA1 pyramidal cells in vitro using chronic treatments (48 h) that either increase (picrotoxin) or decrease (kynurenate) neuronal activity. The h‐conductance was...

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Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Gasselin, Célia, Inglebert, Yanis, Debanne, Dominique
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650411/
https://ncbi.nlm.nih.gov/pubmed/26316265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271369
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