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Homeostatic regulation of h‐conductance controls intrinsic excitability and stabilizes the threshold for synaptic modification in CA1 neurons

KEY POINTS: We determined the contribution of the hyperpolarization‐activated cationic (h) current (I (h)) to the homeostatic regulation of CA1 pyramidal cells in vitro using chronic treatments (48 h) that either increase (picrotoxin) or decrease (kynurenate) neuronal activity. The h‐conductance was...

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Publicat a:J Physiol
Autors principals: Gasselin, Célia, Inglebert, Yanis, Debanne, Dominique
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650411/
https://ncbi.nlm.nih.gov/pubmed/26316265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271369
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