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GABA(B) receptor‐mediated feed‐forward circuit dysfunction in the mouse model of fragile X syndrome

KEY POINTS: Cortico‐hippocampal feed‐forward circuits formed by the temporoammonic (TA) pathway exhibit a marked increase in excitation/inhibition ratio and abnormal spike modulation functions in Fmr1 knock‐out (KO) mice. Inhibitory, but not excitatory, synapse dysfunction underlies cortico‐hippocam...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Wahlstrom‐Helgren, Sarah, Klyachko, Vitaly A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650406/
https://ncbi.nlm.nih.gov/pubmed/26282581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271190
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