The enhanced expression of death receptor 5 (DR5) mediated by HBV X protein through NF-kappaB pathway is associated with cell apoptosis induced by (TNF-α related apoptosis inducing ligand) TRAIL in hepatoma cells

BACKGROUND: HBV X protein (HBX) is associated with cell apoptosis mediated by TNF-α related apoptosis inducing ligand (TRAIL), while the role of HBX on the expressions of TRAIL receptors death receptor 4 (DR4) and DR5 are unclear. In this study, we detected the cell apoptosis induced by TRAIL as wel...

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Publicado en:Virol J
Autores principales: Kong, Fanyun, You, Hongjuan, Zhao, Jinjin, Liu, Wen, Hu, Lei, Luo, Wenya, Hu, Wei, Tang, Renxian, Zheng, Kuiyang
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650207/
https://ncbi.nlm.nih.gov/pubmed/26577955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0416-z
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