Enhancing mammary differentiation by overcoming lineage-specific epigenetic modification and signature gene expression of fibroblast-derived iPSCs

Recent studies have shown that induced pluripotent stem cells (iPSCs) retain a memory of their origin and exhibit biased differentiation potential. This finding reveals a severe limitation in the application of iPSCs to cell-based therapy because it means that certain cell types are not available fo...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Y, Hong, N, Zhang, A, Chen, W, Wang, R-H, Xu, X-L, Deng, C-X
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649828/
https://ncbi.nlm.nih.gov/pubmed/25476898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.499
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