Lipid droplets hypertrophy: a crucial determining factor in insulin regulation by adipocytes

Lipid droplets (LDs) hypertrophy in adipocytes is the main cause of energy metabolic system dysfunction, obesity and its afflictions such as T2D. However, the role of adipocytes in linking energy metabolic disorders with insulin regulation is unknown in humans. Human adipocytes constitutively synthe...

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Publicado no:Sci Rep
Main Authors: Sanjabi, Bahram, Dashty, Monireh, Özcan, Behiye, Akbarkhanzadeh, Vishtaseb, Rahimi, Mehran, Vinciguerra, Manlio, van Rooij, Felix, Al-Lahham, Saad, Sheedfar, Fareeba, van Kooten, Theo G., Spek, C. Arnold, Rowshani, Ajda T., van der Want, Johannes, Klaassen, Rene, Sijbrands, Eric, Peppelenbosch, Maikel P., Rezaee, Farhad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649717/
https://ncbi.nlm.nih.gov/pubmed/25743104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08816
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