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Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma

Improving treatment of advanced melanoma may require the development of effective strategies to overcome resistance to different anti-tumor agents and to counteract relevant pro-tumoral mechanisms in the microenvironment. Here we provide preclinical evidence that these goals can be achieved in most...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Grazia, G, Vegetti, C, Benigni, F, Penna, I, Perotti, V, Tassi, E, Bersani, I, Nicolini, G, Canevari, S, Carlo-Stella, C, Gianni, A M, Mortarini, R, Anichini, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649516/
https://ncbi.nlm.nih.gov/pubmed/25275595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.410
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