Innate resistance of PD-1 blockade through loss of function mutations in JAK resulting in inability to express PD-L1 upon interferon exposure

Lignende værker

• Primary resistance to PD-1 blockade mediated by JAK1/2 mutations
  af: Shin, Daniel Sanghoon, et al.
  Udgivet: (2016)
• Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
  af: Garcia-Diaz, Angel, et al.
  Udgivet: (2017)
• Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
  af: Zaretsky, Jesse M., et al.
  Udgivet: (2016)
• Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
  af: Hugo, Willy, et al.
  Udgivet: (2016)
• Combined treatment with dabrafenib and trametinib with immune-stimulating antibodies for BRAF mutant melanoma
  af: Homet Moreno, Blanca, et al.
  Udgivet: (2015)