Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells

Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types, but it is unclear how global epigenetic changes are regulated during this process. Here, we tested the hypothesis that global chromatin organization affects the lineage potential of stem cells and that...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Ugarte, Fernando, Sousae, Rebekah, Cinquin, Bertrand, Martin, Eric W., Krietsch, Jana, Sanchez, Gabriela, Inman, Margaux, Tsang, Herman, Warr, Matthew, Passegué, Emmanuelle, Larabell, Carolyn A., Forsberg, E. Camilla
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649257/
https://ncbi.nlm.nih.gov/pubmed/26489895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.09.009
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