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Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2′-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases

Norovirus (NoV) is a positive-sense single-stranded RNA virus that causes acute gastroenteritis and is responsible for 200,000 deaths per year worldwide. No effective vaccine or treatment is available. Recent studies have shown that the nucleoside analogs favipiravir (T-705) and 2′-C-methyl-cytidine...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antimicrob Agents Chemother
मुख्य लेखकों: Jin, Zhinan, Tucker, Kathryn, Lin, Xiaoyan, Kao, C. Cheng, Shaw, Ken, Tan, Hua, Symons, Julian, Behera, Ishani, Rajwanshi, Vivek K., Dyatkina, Natalia, Wang, Guangyi, Beigelman, Leo, Deval, Jerome
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649231/
https://ncbi.nlm.nih.gov/pubmed/26392512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01391-15
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