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Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase

Preexposure prophylaxis (PrEP) using antiretroviral drugs is effective in reducing the risk of human immunodeficiency virus type 1 (HIV-1) infection, but adherence to the PrEP regimen is needed. To improve adherence, a long-acting injectable formulation of the nonnucleoside reverse transcriptase (RT...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Melody, Kevin, McBeth, Sarah, Kline, Christopher, Kashuba, Angela D. M., Mellors, John W., Ambrose, Zandrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649225/
https://ncbi.nlm.nih.gov/pubmed/26438501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01937-15
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