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Acquired Multidrug Antifungal Resistance in Candida lusitaniae during Therapy

Candida lusitaniae is usually susceptible to echinocandins. Beta-1,3-glucan synthase encoded by FKS genes is the target of echinocandins. A few missense mutations in the C. lusitaniae FKS1 hot spot 1 (HS1) have been reported. We report here the rapid emergence of antifungal resistance in C. lusitani...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Asner, Sandra A., Giulieri, Stefano, Diezi, Manuel, Marchetti, Oscar, Sanglard, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649199/
https://ncbi.nlm.nih.gov/pubmed/26438490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02204-15
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