Candida albicans Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents

The role of sterol mutations in the resistance of Candida albicans to antifungal agents has not been thoroughly investigated. Previous work reported that clinical C. albicans strains resistant to both azole antifungals and amphotericin B were defective in ERG3, a gene encoding sterol Δ(5,6)-desatura...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sanglard, Dominique, Ischer, Françoise, Parkinson, Tania, Falconer, Derek, Bille, Jacques
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2404-2412.2003
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