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Candida albicans Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents

The role of sterol mutations in the resistance of Candida albicans to antifungal agents has not been thoroughly investigated. Previous work reported that clinical C. albicans strains resistant to both azole antifungals and amphotericin B were defective in ERG3, a gene encoding sterol Δ(5,6)-desatura...

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Autors principals: Sanglard, Dominique, Ischer, Françoise, Parkinson, Tania, Falconer, Derek, Bille, Jacques
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC166068/
https://ncbi.nlm.nih.gov/pubmed/12878497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2404-2412.2003
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