Thymidine-Dependent Staphylococcus aureus Small-Colony Variants Are Induced by Trimethoprim-Sulfamethoxazole (SXT) and Have Increased Fitness during SXT Challenge

Trimethoprim-sulfamethoxazole (SXT) is a possible alternative for the treatment of community- and hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) due to the susceptibility of most MRSA strains to the drug. However, after long-term treatment with SXT, thymidine-dependent (TD) SXT...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Kriegeskorte, Andre, Lorè, Nicola Ivan, Bragonzi, Alessandra, Riva, Camilla, Kelkenberg, Marco, Becker, Karsten, Proctor, Richard A., Peters, Georg, Kahl, Barbara C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649163/
https://ncbi.nlm.nih.gov/pubmed/26369968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00742-15
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