In Vivo Mutations of Thymidylate Synthase (Encoded by thyA) Are Responsible for Thymidine Dependency in Clinical Small-Colony Variants of Staphylococcus aureus

Trimethoprim-sulfamethoxazole (SXT)-resistant Staphylococcus aureus thymidine-dependent small-colony variants (TD-SCVs) are frequently isolated from the airways of cystic fibrosis (CF) patients, often in combination with isogenic normal strains if patients were treated with SXT for extended periods....

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Hlavní autoři: Chatterjee, Indranil, Kriegeskorte, Andre, Fischer, Andreas, Deiwick, Susanne, Theimann, Nadine, Proctor, Richard A., Peters, Georg, Herrmann, Mathias, Kahl, Barbara C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Meeting Presentations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223566/
https://ncbi.nlm.nih.gov/pubmed/17905979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00912-07
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