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Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancer
Irinotecan hydrochloride is a camptothecin derivative that exerts antitumor activity against a variety of tumors. SN-38 produced in the body by carboxylesterase is the active metabolite of irinotecan. After irinotecan was introduced for the treatment of metastatic colorectal cancer (CRC) at the end...
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| Publicado no: | World J Gastroenterol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4649109/ https://ncbi.nlm.nih.gov/pubmed/26604633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i43.12234 |
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