Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens

Cytotoxic T cells recognize, via their T cell receptors (TCRs), small antigenic peptides presented by the major histocompatibility complex (pMHC) on the surface of professional antigen-presenting cells and infected or malignant cells. The efficiency of T cell triggering critically depends on TCR bin...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hebeisen, Michael, Allard, Mathilde, Gannon, Philippe O., Schmidt, Julien, Speiser, Daniel E., Rufer, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649060/
https://ncbi.nlm.nih.gov/pubmed/26635796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00582
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