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Competition between the Brain and Testes under Selenium-Compromised Conditions: Insight into Sex Differences in Selenium Metabolism and Risk of Neurodevelopmental Disease

Selenium (Se) is essential for both brain development and male fertility. Male mice lacking two key genes involved in Se metabolism (Scly(−/−)Sepp1(−/−) mice), selenoprotein P (Sepp1) and Sec lyase (Scly), develop severe neurological dysfunction, neurodegeneration, and audiogenic seizures that manif...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Neurosci
Κύριοι συγγραφείς: Pitts, Matthew W., Kremer, Penny M., Hashimoto, Ann C., Torres, Daniel J., Byrns, China N., Williams, Christopher S., Berry, Marla J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Society for Neuroscience 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649005/
https://ncbi.nlm.nih.gov/pubmed/26586820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2724-15.2015
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