IN VITRO TESTING OF AN ANTI-CD40 MONOCLONAL ANTIBODY, CLONE 2C10, IN PRIMATES AND PIGS

BACKGROUND: The CD40/CD154 and CD28/B7 pathways are important in allo- and xeno-transplantation. Owing to the thrombotic complications of anti-CD154mAb, anti-CD40mAb has emerged as a promising inhibitor of costimulation. Various clones of anti-CD40mAb have been developed against primate species, e.g...

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Publicado en:Transpl Immunol
Autores principales: Lee, Whayoung, Satyananda, Vikas, Iwase, Hayato, Tanaka, Takayuki, Miyagawa, Yuko, Long, Cassandra, Ayares, David, Cooper, David KC, Hara, Hidetaka
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648655/
https://ncbi.nlm.nih.gov/pubmed/26458513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2015.09.007
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