ロード中...
BRAF inhibition generates a host/tumor niche that mediates therapeutic escape
The current study defines a fibroblast-derived niche that facilitates the therapeutic escape of melanoma cells from BRAF inhibition. Vemurafenib treatment led to the release of TGF-β from the melanoma cells that increased the differentiation state of the fibroblasts; an affect associated with fibron...
保存先:
| 出版年: | J Invest Dermatol |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648653/ https://ncbi.nlm.nih.gov/pubmed/26302068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.329 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|