Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells

Despite major advances in understanding the molecular and genetic basis of cancer, metastasis remains the cause of >90% of cancer-related mortality(1). Understanding metastasis initiation and progression is critical to developing new therapeutic strategies to treat and prevent metastatic disease....

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Vydáno v:Nature
Hlavní autoři: Lawson, Devon A., Bhakta, Nirav R., Kessenbrock, Kai, Prummel, Karin D., Yu, Ying, Takai, Ken, Zhou, Alicia, Eyob, Henok, Balakrishnan, Sanjeev, Wang, Chih-Yang, Yaswen, Paul, Goga, Andrei, Werb, Zena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648562/
https://ncbi.nlm.nih.gov/pubmed/26416748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15260
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