Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA

The extent to which heritable genetic variants can affect tumor development has yet to be fully elucidated. Tumor selection of single nucleotide polymorphism (SNP) risk alleles, a phenomenon called preferential allelic imbalance (PAI), has been demonstrated in some cancer types. We developed a novel...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: de Smith, Adam J., Walsh, Kyle M., Hansen, Helen M., Endicott, Alyson A., Wiencke, John K., Metayer, Catherine, Wiemels, Joseph L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648491/
https://ncbi.nlm.nih.gov/pubmed/26575185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143343
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