DNA sequencing: modular primers assembled from a library of hexamers or pentamers.
Here we report a striking effect displayed by "modular primers," which consist of hexamer or pentamer oligonucleotide modules base-stacked to each other upon annealing to a DNA template. Such a combination of modules is found to prime DNA sequencing reactions uniquely, unlike either of the modules a...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8483939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.4241 |
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