Diltiazem augments the influence of MDR1 genotype status on cyclosporine concentration in Chinese patients with renal transplantation

AIM: Co-administration of diltiazem can reduce the dosage of cyclosporine (CsA) in patients with renal transplantation. In this study, we investigated how diltiazem altered the relationship between MDR1 genetic polymorphisms and CsA concentration in Chinese patients with renal transplantation. METHO...

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Detalles Bibliográficos
Publicado en:Acta Pharmacol Sin
Autores principales: Wang, Yi-xi, Li, Jia-li, Wang, Xue-ding, Zhang, Yu, Wang, Chang-xi, Huang, Min
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648117/
https://ncbi.nlm.nih.gov/pubmed/25891084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.6
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