Diltiazem augments the influence of MDR1 genotype status on cyclosporine concentration in Chinese patients with renal transplantation

AIM: Co-administration of diltiazem can reduce the dosage of cyclosporine (CsA) in patients with renal transplantation. In this study, we investigated how diltiazem altered the relationship between MDR1 genetic polymorphisms and CsA concentration in Chinese patients with renal transplantation. METHO...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Wang, Yi-xi, Li, Jia-li, Wang, Xue-ding, Zhang, Yu, Wang, Chang-xi, Huang, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648117/
https://ncbi.nlm.nih.gov/pubmed/25891084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.6
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