Associations of ABCB1, NFKB1, CYP3A, and NR1I2 polymorphisms with cyclosporine trough concentrations in Chinese renal transplant recipients

AIM: Cyclosporine requires close therapeutic drug monitoring because of its narrow therapeutic index and marked inter-individual pharmacokinetic variation. In this study, we investigated the associations of CYP3A4, CYP3A5, ABCB1, NFKB1, and NR1I2 polymorphisms with cyclosporine concentrations in Chi...

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Main Authors: Zhang, Yu, Li, Jia-li, Fu, Qian, Wang, Xue-ding, Liu, Long-shan, Wang, Chang-xi, Xie, Wen, Chen, Zhuo-jia, Shu, Wen-ying, Huang, Min
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002791/
https://ncbi.nlm.nih.gov/pubmed/23503472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.200
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