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Inhibition of Na(v)1.7 channels by methyl eugenol as a mechanism underlying its antinociceptive and anesthetic actions

AIM: Methyl eugenol is a major active component extracted from the Chinese herb Asari Radix et Rhizoma, which has been used to treat toothache and other pain. Previous in vivo studies have shown that methyl eugenol has anesthetic and antinociceptive effects. The aim of this study was to determine th...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Wang, Ze-Jun, Tabakoff, Boris, Levinson, Simon R, Heinbockel, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648112/
https://ncbi.nlm.nih.gov/pubmed/26051112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.26
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