Role of KRAS-LCS6 polymorphism in advanced NSCLC patients treated with erlotinib or docetaxel in second line treatment (TAILOR)

MicroRNAs were described to target mRNA and regulate the transcription of genes involved in processes de-regulated in tumorigenesis, such as proliferation, differentiation and survival. In particular, the miRNA let-7 has been suggested to regulate the expression of the KRAS gene, a common mutated ge...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ganzinelli, Monica, Rulli, Eliana, Caiola, Elisa, Chiara Garassino, Marina, Broggini, Massimo, Copreni, Elena, Piva, Sheila, Longo, Flavia, Labianca, Roberto, Bareggi, Claudia, Agnese Fabbri, Maria, Martelli, Olga, Fagnani, Daniele, Cristina Locatelli, Maria, Bertolini, Alessandro, Valmadre, Giuseppe, Pavese, Ida, Calcagno, Anna, Giuseppa Sarobba, Maria, Marabese, Mirko
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648064/
https://ncbi.nlm.nih.gov/pubmed/26573509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16331
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