Role of KRAS-LCS6 polymorphism in advanced NSCLC patients treated with erlotinib or docetaxel in second line treatment (TAILOR)

MicroRNAs were described to target mRNA and regulate the transcription of genes involved in processes de-regulated in tumorigenesis, such as proliferation, differentiation and survival. In particular, the miRNA let-7 has been suggested to regulate the expression of the KRAS gene, a common mutated ge...

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Pubblicato in:Sci Rep
Autori principali: Ganzinelli, Monica, Rulli, Eliana, Caiola, Elisa, Chiara Garassino, Marina, Broggini, Massimo, Copreni, Elena, Piva, Sheila, Longo, Flavia, Labianca, Roberto, Bareggi, Claudia, Agnese Fabbri, Maria, Martelli, Olga, Fagnani, Daniele, Cristina Locatelli, Maria, Bertolini, Alessandro, Valmadre, Giuseppe, Pavese, Ida, Calcagno, Anna, Giuseppa Sarobba, Maria, Marabese, Mirko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648064/
https://ncbi.nlm.nih.gov/pubmed/26573509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16331
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