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Enantioselective Synthesis of Spiroindenes by Enol-Directed Rhodium(III)-Catalyzed C–H Functionalization and Spiroannulation

Chiral cyclopentadienyl rhodium complexes promote highly enantioselective enol-directed C(sp(2))-H functionalization and oxidative annulation with alkynes to give spiroindenes containing all-carbon quaternary stereocenters. High selectivity between two possible directing groups, as well as control o...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Reddy Chidipudi, Suresh, Burns, David J, Khan, Imtiaz, Lam, Hon Wai
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648053/
https://ncbi.nlm.nih.gov/pubmed/26404643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507029
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