Loss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression

BACKGROUND: The biological significance of FOXO1, a member of the forkhead box O transcription factor family, in gastric cancer (GC) remains unclear. The present study provides direct evidence of the role of FOXO1 in tumour growth and metastasis of GC in relation to human epidermal growth factor rec...

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Publicat a:Br J Cancer
Autors principals: Ko, Young San, Cho, Sung Jin, Park, Jinju, Kim, Younghoon, Choi, Yong Joon, Pyo, Jung-Soo, Jang, Bo Gun, Park, Jong-Wan, Kim, Woo Ho, Lee, Byung Lan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647872/
https://ncbi.nlm.nih.gov/pubmed/26448177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.273
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