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Loss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression

BACKGROUND: The biological significance of FOXO1, a member of the forkhead box O transcription factor family, in gastric cancer (GC) remains unclear. The present study provides direct evidence of the role of FOXO1 in tumour growth and metastasis of GC in relation to human epidermal growth factor rec...

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Bibliografiske detaljer
Udgivet i:Br J Cancer
Main Authors: Ko, Young San, Cho, Sung Jin, Park, Jinju, Kim, Younghoon, Choi, Yong Joon, Pyo, Jung-Soo, Jang, Bo Gun, Park, Jong-Wan, Kim, Woo Ho, Lee, Byung Lan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647872/
https://ncbi.nlm.nih.gov/pubmed/26448177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.273
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