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Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein

BACKGROUND: BRF2 is a transcription factor required for synthesis of a small group of non-coding RNAs by RNA polymerase III. Overexpression of BRF2 can transform human mammary epithelial cells. In both breast and lung cancers, the BRF2 gene is amplified and overexpressed and may serve as an oncogeni...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Koo, Jana, Cabarcas-Petroski, Stephanie, Petrie, John L., Diette, Nicole, White, Robert J., Schramm, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647806/
https://ncbi.nlm.nih.gov/pubmed/26573593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1914-5
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